diff --git a/pkgs/development/python-modules/aiospinel/default.nix b/pkgs/development/python-modules/aiospinel/default.nix
new file mode 100644
index 000000000000..1e5156451762
--- /dev/null
+++ b/pkgs/development/python-modules/aiospinel/default.nix
@@ -0,0 +1,55 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  setuptools,
+  setuptools-scm,
+  typing-extensions,
+  pytestCheckHook,
+  pytest-asyncio,
+  pytest-cov-stub,
+  pytest-timeout,
+}:
+
+buildPythonPackage (finalAttrs: {
+  pname = "aiospinel";
+  version = "1.2.0";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "home-assistant-libs";
+    repo = "aiospinel";
+    tag = "v${finalAttrs.version}";
+    hash = "sha256-AMIrm9AGFjRSDwJtDXcOH9HIBFiqszjjNma+egRa5Tw=";
+  };
+
+  build-system = [
+    setuptools
+    setuptools-scm
+  ];
+
+  dependencies = [
+    typing-extensions
+  ];
+
+  nativeCheckInputs = [
+    pytestCheckHook
+    pytest-asyncio
+    pytest-cov-stub
+    pytest-timeout
+  ];
+
+  pythonImportsCheck = [
+    "aiospinel"
+  ];
+
+  __structuredAttrs = true;
+
+  meta = {
+    description = "Asyncio implementation of the Spinel protocol used to communicate with OpenThread RCPs over a serial connection";
+    homepage = "https://github.com/home-assistant-libs/aiospinel";
+    changelog = "https://github.com/home-assistant-libs/aiospinel/releases/tag/${finalAttrs.src.tag}";
+    license = lib.licenses.asl20;
+    maintainers = with lib.maintainers; [ hexa ];
+  };
+})
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index f792d912e4dc..0e296171383b 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -560,6 +560,8 @@ self: super: with self; {
 
   aiosonos = callPackage ../development/python-modules/aiosonos { };
 
+  aiospinel = callPackage ../development/python-modules/aiospinel { };
+
   aiosql = callPackage ../development/python-modules/aiosql { };
 
   aiosqlite = callPackage ../development/python-modules/aiosqlite { };