diff --git a/pkgs/development/interpreters/python/hooks/default.nix b/pkgs/development/interpreters/python/hooks/default.nix
index 903ad0215cdf..5d605b240ad8 100644
--- a/pkgs/development/interpreters/python/hooks/default.nix
+++ b/pkgs/development/interpreters/python/hooks/default.nix
@@ -92,8 +92,9 @@ in rec {
   pythonCatchConflictsHook = callPackage ({ setuptools }:
     makeSetupHook {
       name = "python-catch-conflicts-hook";
+      deps = [ setuptools ];
       substitutions = {
-        inherit pythonInterpreter pythonSitePackages setuptools;
+        inherit pythonInterpreter;
         catchConflicts=../catch_conflicts/catch_conflicts.py;
       };
     } ./python-catch-conflicts-hook.sh) {};
diff --git a/pkgs/development/interpreters/python/hooks/python-catch-conflicts-hook.sh b/pkgs/development/interpreters/python/hooks/python-catch-conflicts-hook.sh
index 0abcad3c42f2..374a2eddb407 100644
--- a/pkgs/development/interpreters/python/hooks/python-catch-conflicts-hook.sh
+++ b/pkgs/development/interpreters/python/hooks/python-catch-conflicts-hook.sh
@@ -2,7 +2,7 @@
 echo "Sourcing python-catch-conflicts-hook.sh"
 
 pythonCatchConflictsPhase() {
-    PYTHONPATH="@setuptools@/@pythonSitePackages@:$PYTHONPATH" @pythonInterpreter@ @catchConflicts@
+    @pythonInterpreter@ @catchConflicts@
 }
 
 if [ -z "${dontUsePythonCatchConflicts-}" ]; then
diff --git a/pkgs/development/interpreters/python/mk-python-derivation.nix b/pkgs/development/interpreters/python/mk-python-derivation.nix
index a032c08d2a82..f37ad592cb49 100644
--- a/pkgs/development/interpreters/python/mk-python-derivation.nix
+++ b/pkgs/development/interpreters/python/mk-python-derivation.nix
@@ -121,7 +121,7 @@ let
       ensureNewerSourcesForZipFilesHook  # move to wheel installer (pip) or builder (setuptools, flit, ...)?
       pythonRemoveTestsDirHook
     ] ++ lib.optionals catchConflicts [
-      pythonCatchConflictsHook
+      setuptools pythonCatchConflictsHook
     ] ++ lib.optionals removeBinBytecode [
       pythonRemoveBinBytecodeHook
     ] ++ lib.optionals (lib.hasSuffix "zip" (attrs.src.name or "")) [