diff --git a/pkgs/misc/emulators/wine/base.nix b/pkgs/misc/emulators/wine/base.nix
index 0023d9878b36..49de366875cf 100644
--- a/pkgs/misc/emulators/wine/base.nix
+++ b/pkgs/misc/emulators/wine/base.nix
@@ -74,7 +74,7 @@ stdenv.mkDerivation ((lib.optionalAttrs (buildScript != null) {
   ++ lib.optionals openclSupport [ pkgs.opencl-headers pkgs.ocl-icd ]
   ++ lib.optionals xmlSupport    [ pkgs.libxml2 pkgs.libxslt ]
   ++ lib.optionals tlsSupport    [ pkgs.openssl pkgs.gnutls ]
-  ++ lib.optionals openglSupport [ pkgs.libGLU pkgs.libGL pkgs.mesa.osmesa pkgs.libdrm ]
+  ++ lib.optionals (openglSupport && !stdenv.isDarwin) [ pkgs.libGLU pkgs.libGL pkgs.mesa.osmesa pkgs.libdrm ]
   ++ lib.optionals stdenv.isDarwin (with pkgs.buildPackages.darwin.apple_sdk.frameworks; [
      CoreServices Foundation ForceFeedback AppKit OpenGL IOKit DiskArbitration Security
      ApplicationServices AudioToolbox CoreAudio AudioUnit CoreMIDI OpenAL OpenCL Cocoa Carbon