diff --git a/pkgs/development/web/nodejs/fix-libuv-1.53-support.patch b/pkgs/development/web/nodejs/fix-libuv-1.53-support.patch
new file mode 100644
index 000000000000..b446b11fbe81
--- /dev/null
+++ b/pkgs/development/web/nodejs/fix-libuv-1.53-support.patch
@@ -0,0 +1,62 @@
+Extracted from https://github.com/nodejs/node/pull/66282
+
+diff --git a/src/node_sockaddr.cc b/src/node_sockaddr.cc
+index 3f903f548e17..7c2285de32dd 100644
+--- a/src/node_sockaddr.cc
++++ b/src/node_sockaddr.cc
+@@ -1046,8 +1046,8 @@ bool SocketAddressBlockListWrap::FastCheckString(
+   // FastOneByteString is not NUL-terminated. Copy onto the stack
+   // before any other work: a GC would invalidate `address`.
+   //
+-  // uv_ip6_addr only needs the address part (≤39 chars) plus an
+-  // optional %zone. A zone longer than UV_IF_NAMESIZE is unknown
++  // uv_ip6_addr only needs the address part (< INET6_ADDRSTRLEN chars)
++  // plus an optional %zone. A zone longer than UV_IF_NAMESIZE is unknown
+   // (scope_id 0), same as omitting it. Keep that behavior when the
+   // full string does not fit so Fast API and CheckString agree.
+   constexpr size_t kMax = INET6_ADDRSTRLEN + UV_IF_NAMESIZE;
+@@ -1058,14 +1058,14 @@ bool SocketAddressBlockListWrap::FastCheckString(
+   } else if (family == AF_INET6) {
+     // uv_ip4_addr rejects %zone. Only IPv6 may drop an overlong zone
+     // (unknown zone → scope_id 0, same as uv_ip6_addr).
+-    // uv_ip6_addr copies the address part into a 40-byte buffer
+-    // (39 chars + NUL). A 40+ char prefix (mixed notation) is
+-    // truncated and fails inet_pton — do not keep the full prefix.
++    // uv_ip6_addr copies the address part into an INET6_ADDRSTRLEN
++    // buffer and truncates a longer one to INET6_ADDRSTRLEN - 1 chars
++    // before inet_pton. Do the same so both paths parse the same prefix.
+     const char* percent =
+         static_cast<const char*>(memchr(address.data, '%', address.length));
+     if (percent == nullptr) return false;
+-    const size_t addr_len = static_cast<size_t>(percent - address.data);
+-    if (addr_len >= 40) return false;
++    size_t addr_len = static_cast<size_t>(percent - address.data);
++    if (addr_len >= INET6_ADDRSTRLEN) addr_len = INET6_ADDRSTRLEN - 1;
+     memcpy(buf, address.data, addr_len);
+     buf[addr_len] = '\0';
+   } else {
+diff --git a/test/parallel/test-blocklist.js b/test/parallel/test-blocklist.js
+index b0fe4303bfb2..c548917b1c77 100644
+--- a/test/parallel/test-blocklist.js
++++ b/test/parallel/test-blocklist.js
+@@ -883,12 +883,17 @@ const util = require('util');
+   blockList.addAddress('1.1.1.1');
+   assert.strictEqual(blockList.check(`1.1.1.1%${'z'.repeat(200)}`), false);
+ 
+-  // Mixed-notation IPv6 is 45 chars. uv_ip6_addr truncates the
+-  // address part to 39 when a zone is present, so this is a miss.
++  // Mixed-notation IPv6 is 45 chars. uv_ip6_addr keeps up to
++  // INET6_ADDRSTRLEN - 1 chars of the address part when a zone is
++  // present, so this is a hit on libuv 1.53+.
+   const mixed = 'ffff:ffff:ffff:ffff:ffff:ffff:255.255.255.255';
+   blockList.addAddress(mixed, 'ipv6');
+   assert.strictEqual(blockList.check(mixed, 'ipv6'), true);
+-  assert.strictEqual(blockList.check(`${mixed}%${'z'.repeat(200)}`, 'ipv6'), false);
++  const isModernLibuv = ((versionString) => {
++    const [major, minor] = versionString.split('.', 2).map(Number);
++    return major >= 1 && minor >= 53;
++  })(process.versions.uv);
++  assert.strictEqual(blockList.check(`${mixed}%${'z'.repeat(200)}`, 'ipv6'), isModernLibuv);
+ }
+ 
+ // check() family parameter is case-insensitive.
diff --git a/pkgs/development/web/nodejs/v26.nix b/pkgs/development/web/nodejs/v26.nix
index fde53e108b69..a9d83fe617b0 100644
--- a/pkgs/development/web/nodejs/v26.nix
+++ b/pkgs/development/web/nodejs/v26.nix
@@ -50,6 +50,9 @@ buildNodejs {
 
       # https://github.com/NixOS/nixpkgs/issues/568974
       ./memcpy-climits.patch
+
+      # TODO: remove once support for libuv 1.53+ has landed upstream
+      ./fix-libuv-1.53-support.patch
     ]
     ++ gypPatches;
 }