diff --git a/pkgs/development/python-modules/ckzg/default.nix b/pkgs/development/python-modules/ckzg/default.nix
new file mode 100644
index 000000000000..135c354d1224
--- /dev/null
+++ b/pkgs/development/python-modules/ckzg/default.nix
@@ -0,0 +1,60 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  setuptools,
+  clang,
+  # dependencies
+  pyyaml,
+  blst,
+  # checkPhase dependencies
+  python,
+}:
+
+buildPythonPackage rec {
+  pname = "ckzg";
+  version = "2.0.1";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "ethereum";
+    repo = "c-kzg-4844";
+    tag = "v${version}";
+    hash = "sha256-kOoodri80p5tz8RlMz6mqsZRAuXBxZm4vr+VWJEtfA0=";
+  };
+
+  build-system = [ setuptools ];
+
+  nativeBuildInputs = [ clang ];
+
+  dependencies = [
+    pyyaml
+    blst
+  ];
+
+  postPatch =
+    # unvendor "blst"
+    ''
+      substituteInPlace setup.py \
+        --replace-fail '"build_ext": CustomBuild,' ""
+    '';
+
+  checkPhase = ''
+    runHook preCheck
+
+    cd bindings/python
+    ${python.interpreter} tests.py
+
+    runHook postCheck
+  '';
+
+  pythonImportsCheck = [ "ckzg" ];
+
+  meta = {
+    description = "Minimal implementation of the Polynomial Commitments API for EIP-4844 and EIP-7594";
+    homepage = "https://github.com/ethereum/c-kzg-4844";
+    changelog = "https://github.com/ethereum/c-kzg-4844/releases/tag/v${version}";
+    license = lib.licenses.asl20;
+    maintainers = with lib.maintainers; [ hellwolf ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index c0b4b6e5bfd4..77018732cb41 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -2332,6 +2332,8 @@ self: super: with self; {
 
   ckcc-protocol = callPackage ../development/python-modules/ckcc-protocol { };
 
+  ckzg = callPackage ../development/python-modules/ckzg { };
+
   clarabel = callPackage ../development/python-modules/clarabel { };
 
   clarifai = callPackage ../development/python-modules/clarifai { };