diff --git a/pkgs/tools/misc/kargo/default.nix b/pkgs/tools/misc/kargo/default.nix
deleted file mode 100644
index 15310fb9350a..000000000000
--- a/pkgs/tools/misc/kargo/default.nix
+++ /dev/null
@@ -1,39 +0,0 @@
-{ lib, fetchurl, python3Packages }:
-
-with python3Packages;
-
-buildPythonApplication rec {
-  version = "0.4.8";
-  pname = "kargo";
-
-  src = fetchurl {
-    url = "mirror://pypi/k/kargo/${pname}-${version}.tar.gz";
-    sha256 = "1iq3vrmglag9gpsir03yz7556m0bz99nwb2mf594378cqzbr6db3";
-  };
-
-  propagatedBuildInputs = [
-    ansible-core
-    boto
-    cffi
-    cryptography
-    libcloud
-    markupsafe
-    netaddr
-    pyasn1
-    requests
-    setuptools
-  ];
-
-  checkPhase = ''
-    HOME=$TMPDIR $out/bin/kargo -v
-  '';
-
-  meta = with lib; {
-    homepage = "https://github.com/kubespray/kargo-cli";
-    description = "Tool helps to deploy a kubernetes cluster with Ansible";
-    platforms = platforms.all;
-    license = licenses.gpl3;
-    maintainers = [ ];
-    mainProgram = "kargo";
-  };
-}
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 97db40c618c4..264c231fa20f 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -756,6 +756,7 @@ mapAliases ({
   kube3d = k3d; # Added 2022-0705
   kafkacat = kcat; # Added 2021-10-07
   kak-lsp = kakoune-lsp; # Added 2024-04-01
+  kargo = throw "kargo was removed as it is deprecated upstream and depends on the removed boto package"; # Added 2024-09-22
   kdbplus = throw "'kdbplus' has been removed from nixpkgs"; # Added 2024-05-06
   kdeconnect = plasma5Packages.kdeconnect-kde; # Added 2020-10-28
   keepassx = throw "KeePassX is no longer actively developed. Please consider KeePassXC as a maintained alternative."; # Added 2023-02-17
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index e6a9415175ee..f41e712c6e30 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -9038,8 +9038,6 @@ with pkgs;
 
   k2pdfopt = callPackage ../applications/misc/k2pdfopt { };
 
-  kargo = callPackage ../tools/misc/kargo { };
-
   kazam = callPackage ../applications/video/kazam { };
 
   kalibrate-rtl = callPackage ../applications/radio/kalibrate-rtl { };