diff --git a/pkgs/development/python-modules/meld3/default.nix b/pkgs/development/python-modules/meld3/default.nix
deleted file mode 100644
index cc67de2ee01c..000000000000
--- a/pkgs/development/python-modules/meld3/default.nix
+++ /dev/null
@@ -1,24 +0,0 @@
-{
-  lib,
-  buildPythonPackage,
-  fetchPypi,
-}:
-
-buildPythonPackage rec {
-  pname = "meld3";
-  version = "2.0.1";
-  format = "setuptools";
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "3ea266994f1aa83507679a67b493b852c232a7905e29440a6b868558cad5e775";
-  };
-
-  doCheck = false;
-
-  meta = {
-    description = "HTML/XML templating engine used by supervisor";
-    homepage = "https://github.com/supervisor/meld3";
-    license = lib.licenses.free;
-  };
-}
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index fd1601785079..d4e748b90c7d 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -369,6 +369,7 @@ mapAliases {
   mdformat-tables = "'mdformat-tables' has been archived and replaced by 'mdformat-gfm"; # added 2025-01-25
   MDP = throw "'MDP' has been renamed to/replaced by 'mdp'"; # Converted to throw 2025-10-29
   MechanicalSoup = throw "'MechanicalSoup' has been renamed to/replaced by 'mechanicalsoup'"; # Converted to throw 2025-10-29
+  meld3 = throw "'meld3' has been removed because it was unused and unmaintained upstream"; # added 2026-06-08
   memcached = throw "'memcached' has been renamed to/replaced by 'python-memcached'"; # Converted to throw 2025-10-29
   memory_profiler = throw "'memory_profiler' has been renamed to/replaced by 'memory-profiler'"; # Converted to throw 2025-10-29
   mesa = throw "python3Packages.mesa has been removed because it has been marked as broken since at least November 2024."; # Added 2025-10-03
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index f5f981ffcbe7..8f7165a3f3e8 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -10308,8 +10308,6 @@ self: super: with self; {
 
   meinheld = callPackage ../development/python-modules/meinheld { };
 
-  meld3 = callPackage ../development/python-modules/meld3 { };
-
   melnor-bluetooth = callPackage ../development/python-modules/melnor-bluetooth { };
 
   memestra = callPackage ../development/python-modules/memestra { };