diff --git a/pkgs/desktops/gnome/extensions/default.nix b/pkgs/desktops/gnome/extensions/default.nix
index 0e4975f40a94..c1abb5bcc152 100644
--- a/pkgs/desktops/gnome/extensions/default.nix
+++ b/pkgs/desktops/gnome/extensions/default.nix
@@ -66,15 +66,6 @@ let
 in
 rec {
   # Remember to import all these in all-packages.nix
-  gnome38Extensions = mapUuidNames (produceExtensionsList "38");
-  gnome40Extensions = mapUuidNames (produceExtensionsList "40");
-  gnome41Extensions = mapUuidNames (produceExtensionsList "41");
-  gnome42Extensions = mapUuidNames (produceExtensionsList "42");
-  gnome43Extensions = mapUuidNames (produceExtensionsList "43");
-  gnome44Extensions = mapUuidNames (produceExtensionsList "44");
-  gnome45Extensions = mapUuidNames (produceExtensionsList "45");
-  gnome46Extensions = mapUuidNames (produceExtensionsList "46");
-  gnome47Extensions = mapUuidNames (produceExtensionsList "47");
   gnome48Extensions = mapUuidNames (produceExtensionsList "48");
   gnome49Extensions = mapUuidNames (produceExtensionsList "49");
   gnome50Extensions = mapUuidNames (produceExtensionsList "50");
diff --git a/pkgs/desktops/gnome/extensions/update-extensions.py b/pkgs/desktops/gnome/extensions/update-extensions.py
index c26433e0a936..478f1483ac16 100755
--- a/pkgs/desktops/gnome/extensions/update-extensions.py
+++ b/pkgs/desktops/gnome/extensions/update-extensions.py
@@ -23,15 +23,6 @@ from typing import Any
 # We don't want all those deprecated legacy extensions
 # Group extensions by GNOME "major" version for compatibility reasons
 supported_versions = {
-    "38": "3.38",
-    "40": "40",
-    "41": "41",
-    "42": "42",
-    "43": "43",
-    "44": "44",
-    "45": "45",
-    "46": "46",
-    "47": "47",
     "48": "48",
     "49": "49",
     "50": "50",
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index f5d1e3ca68b5..0549d5530b3d 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -1054,6 +1054,15 @@ mapAliases {
   gnome2.libgtksourceview = throw "gnome2.libgtksourceview has been removed as it was unmaintained upstream and depended on the deprecated GTK2 engine. Consider using gtksourceview3, gtksourceview4, or gtksourceview5 instead."; # Added 2026-07-23
   gnome2.libIDL = throw "gnome2.libIDL has been removed as it has been archived upstream since July 2014"; # Added 2026-07-23
   gnome2.ORBit2 = throw "gnome2.ORBit2 has been removed as it has been archived upstream since July 2016"; # Added 2026-07-23
+  gnome38Extensions = throw "'gnome38Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 38"; # Added 2026-09-27
+  gnome40Extensions = throw "'gnome40Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 40"; # Added 2026-09-27
+  gnome41Extensions = throw "'gnome41Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 41"; # Added 2026-09-27
+  gnome42Extensions = throw "'gnome42Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 42"; # Added 2026-09-27
+  gnome43Extensions = throw "'gnome43Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 43"; # Added 2026-09-27
+  gnome44Extensions = throw "'gnome44Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 44"; # Added 2026-09-27
+  gnome45Extensions = throw "'gnome45Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 45"; # Added 2026-09-27
+  gnome46Extensions = throw "'gnome46Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 46"; # Added 2026-09-27
+  gnome47Extensions = throw "'gnome47Extensions' has been removed as this package set contained GNOME extensions for the unsupported GNOME Shell version 47"; # Added 2026-09-27
   gnome-bluetooth_1_0 = throw "'gnome-bluetooth_1_0' has been removed as it is unmaintained upstream"; # Added 2026-03-09
   gnome-firmware-updater = throw "'gnome-firmware-updater' has been renamed to/replaced by 'gnome-firmware'"; # Converted to throw 2025-10-27
   gnome-icon-theme = throw "'gnome-icon-theme' has been removed because it is unmaintained upstream and depends on GTK 2."; # Added 2026-07-22
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 4cce505519d7..5b633d7aff05 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -9919,15 +9919,6 @@ with pkgs;
 
   inherit (callPackage ../desktops/gnome/extensions { })
     gnomeExtensions
-    gnome38Extensions
-    gnome40Extensions
-    gnome41Extensions
-    gnome42Extensions
-    gnome43Extensions
-    gnome44Extensions
-    gnome45Extensions
-    gnome46Extensions
-    gnome47Extensions
     gnome48Extensions
     gnome49Extensions
     gnome50Extensions