diff --git a/pkgs/by-name/mo/mouser/package.nix b/pkgs/by-name/mo/mouser/package.nix
index e51d8b9c2544..aa1df49cb9b4 100644
--- a/pkgs/by-name/mo/mouser/package.nix
+++ b/pkgs/by-name/mo/mouser/package.nix
@@ -3,6 +3,7 @@
   stdenv,
   fetchFromGitHub,
   python3Packages,
+  qt6,
   copyDesktopItems,
   makeDesktopItem,
   nix-update-script,
@@ -24,10 +25,25 @@ python3Packages.buildPythonApplication (finalAttrs: {
     hash = "sha256-Pjcx7YChgu7R8Kdv8fOJcxq98nwh/izpjbOO+4/cdk4=";
   };
 
-  nativeBuildInputs = lib.optionals stdenv.hostPlatform.isLinux [
+  nativeBuildInputs = [
+    qt6.wrapQtAppsHook
+  ]
+  ++ lib.optionals stdenv.hostPlatform.isLinux [
     copyDesktopItems
   ];
 
+  # pyside6 does not bundle Qt's QML modules or plugins the way the PyPI
+  # wheel does, so the QtQuick imports and the SVG image/icon plugins must be
+  # provided here for wrapQtAppsHook to pick up.
+  buildInputs = [
+    qt6.qtbase
+    qt6.qtdeclarative
+    qt6.qtsvg
+  ]
+  ++ lib.optionals stdenv.hostPlatform.isLinux [
+    qt6.qtwayland
+  ];
+
   dependencies =
     (with python3Packages; [
       pyside6
@@ -89,8 +105,11 @@ python3Packages.buildPythonApplication (finalAttrs: {
     runHook postInstall
   '';
 
+  # The wrapper is created manually below; there is no binary for the hook to wrap.
+  dontWrapQtApps = true;
+
   postFixup = ''
-    makeWrapper ${python3Packages.python.interpreter} $out/bin/mouser \
+    makeQtWrapper ${python3Packages.python.interpreter} $out/bin/mouser \
       --prefix PYTHONPATH : "$PYTHONPATH" \
   ''
   + lib.optionalString stdenv.hostPlatform.isLinux ''