diff --git a/nixos/tests/all-tests.nix b/nixos/tests/all-tests.nix
index 52637202b19c..970046e98a0a 100644
--- a/nixos/tests/all-tests.nix
+++ b/nixos/tests/all-tests.nix
@@ -359,6 +359,7 @@ in
   php = handleTest ./php {};
   php74 = handleTest ./php { php = pkgs.php74; };
   php80 = handleTest ./php { php = pkgs.php80; };
+  php81 = handleTest ./php { php = pkgs.php81; };
   pinnwand = handleTest ./pinnwand.nix {};
   plasma5 = handleTest ./plasma5.nix {};
   plasma5-systemd-start = handleTest ./plasma5-systemd-start.nix {};
diff --git a/pkgs/development/interpreters/php/8.1.nix b/pkgs/development/interpreters/php/8.1.nix
new file mode 100644
index 000000000000..72d00639b622
--- /dev/null
+++ b/pkgs/development/interpreters/php/8.1.nix
@@ -0,0 +1,51 @@
+{ callPackage, lib, stdenv, ... }@_args:
+
+let
+  base = callPackage ./generic.nix (_args // {
+    version = "8.1.6";
+    sha256 = "ezUzBLdAdVT3DT4QGiJqH8It7K5cTELtJwxOOJv6G2Y=";
+  });
+
+in
+base.withExtensions ({ all, ... }: with all; ([
+  bcmath
+  calendar
+  curl
+  ctype
+  dom
+  exif
+  fileinfo
+  filter
+  ftp
+  gd
+  gettext
+  gmp
+  iconv
+  intl
+  ldap
+  mbstring
+  mysqli
+  mysqlnd
+  opcache
+  openssl
+  pcntl
+  pdo
+  pdo_mysql
+  pdo_odbc
+  pdo_pgsql
+  pdo_sqlite
+  pgsql
+  posix
+  readline
+  session
+  simplexml
+  sockets
+  soap
+  sodium
+  sqlite3
+  tokenizer
+  xmlreader
+  xmlwriter
+  zip
+  zlib
+] ++ lib.optionals (!stdenv.isDarwin) [ imap ]))
diff --git a/pkgs/development/interpreters/php/fix-tokenizer-php81.patch b/pkgs/development/interpreters/php/fix-tokenizer-php81.patch
new file mode 100644
index 000000000000..b43eeefa3c28
--- /dev/null
+++ b/pkgs/development/interpreters/php/fix-tokenizer-php81.patch
@@ -0,0 +1,12 @@
+diff --git a/ext/tokenizer/Makefile.frag b/ext/tokenizer/Makefile.frag
+index 745cbfce91..07bace6022 100644
+--- a/ext/tokenizer/Makefile.frag
++++ b/ext/tokenizer/Makefile.frag
+@@ -1,5 +1,5 @@
+-$(top_srcdir)/ext/tokenizer/tokenizer_data.c: $(top_srcdir)/Zend/zend_language_parser.y
++$(top_srcdir)/tokenizer_data.c: $(top_srcdir)/../../Zend/zend_language_parser.y
+ 	@if test ! -z "$(PHP)"; then \
+ 		$(PHP) $(srcdir)/tokenizer_data_gen.php; \
+ 	fi;
+-$(builddir)/tokenizer.lo: $(top_srcdir)/Zend/zend_language_parser.c $(top_srcdir)/Zend/zend_language_scanner.c
++$(builddir)/tokenizer.lo: $(top_srcdir)/../../Zend/zend_language_parser.c $(top_srcdir)/../../Zend/zend_language_scanner.c
diff --git a/pkgs/development/php-packages/apcu/default.nix b/pkgs/development/php-packages/apcu/default.nix
index 0cfc7b4b44fd..150c761ae511 100644
--- a/pkgs/development/php-packages/apcu/default.nix
+++ b/pkgs/development/php-packages/apcu/default.nix
@@ -3,8 +3,8 @@
 buildPecl {
   pname = "apcu";
 
-  version = "5.1.20";
-  sha256 = "sha256-uZ1A+v7Ab00TL87lPnUm3b/B0EHqbgThc4nfrSj5w5A=";
+  version = "5.1.21";
+  sha256 = "sha256-EDNTBEhpbufK3shQUPbfUTX7EzAHLvKnRWk5Ks/s+8E=";
 
   buildInputs = [ pcre2 ];
   doCheck = true;
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index c3578924fde3..76cc5f30e2e4 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -13544,6 +13544,13 @@ with pkgs;
   phpExtensions = php.extensions;
   phpPackages = php.packages;
 
+  # Import PHP81 interpreter, extensions and packages
+  php81 = callPackage ../development/interpreters/php/8.1.nix {
+    stdenv = if stdenv.cc.isClang then llvmPackages.stdenv else stdenv;
+  };
+  php81Extensions = recurseIntoAttrs php81.extensions;
+  php81Packages = recurseIntoAttrs php81.packages;
+
   # Import PHP80 interpreter, extensions and packages
   php80 = callPackage ../development/interpreters/php/8.0.nix {
     stdenv = if stdenv.cc.isClang then llvmPackages.stdenv else stdenv;
diff --git a/pkgs/top-level/php-packages.nix b/pkgs/top-level/php-packages.nix
index 0aefbeee4e0a..bb30a46b8ca7 100644
--- a/pkgs/top-level/php-packages.nix
+++ b/pkgs/top-level/php-packages.nix
@@ -538,14 +538,21 @@ lib.makeScope pkgs.newScope (self: with self; {
             ++ lib.optionals (lib.versionOlder php.version "7.4") [ "--with-libxml-dir=${libxml2.dev}" ];
           doCheck = false;
         }
-        { name = "sockets"; doCheck = false; }
+        {
+          name = "sockets";
+          doCheck = false;
+        }
         { name = "sodium"; buildInputs = [ libsodium ]; }
         { name = "sqlite3"; buildInputs = [ sqlite ]; }
         { name = "sysvmsg"; }
         { name = "sysvsem"; }
         { name = "sysvshm"; }
         { name = "tidy"; configureFlags = [ "--with-tidy=${html-tidy}" ]; doCheck = false; }
-        { name = "tokenizer"; }
+        {
+          name = "tokenizer";
+          patches = lib.optional (lib.versionAtLeast php.version "8.1")
+            ../development/interpreters/php/fix-tokenizer-php81.patch;
+        }
         {
           name = "wddx";
           buildInputs = [ libxml2 ];