diff --git a/pkgs/development/python-modules/mypy-boto3/default.nix b/pkgs/development/python-modules/mypy-boto3/default.nix
index c0f14ae61f89..6c6b957a15df 100644
--- a/pkgs/development/python-modules/mypy-boto3/default.nix
+++ b/pkgs/development/python-modules/mypy-boto3/default.nix
@@ -443,8 +443,8 @@ in
       "sha256-dXNkOcMonYrBh4yzeubd+v3mW42s9XpmpfvgbtgoJgY=";
 
   mypy-boto3-ec2 =
-    buildMypyBoto3Package "ec2" "1.43.46"
-      "sha256-XDJPpDHlw2q0YJGM9SMsBd/Ww2JWiAsq+5xulibZCJs=";
+    buildMypyBoto3Package "ec2" "1.43.59"
+      "sha256-cAk90nXgbA1YkS9DQr+oM/zJH1+1p5V5g/nlG+Fo3i0=";
 
   mypy-boto3-ec2-instance-connect =
     buildMypyBoto3Package "ec2-instance-connect" "1.43.0"