diff --git a/pkgs/by-name/pd/pdfium/darwin-27-failing-embedder-tests.txt b/pkgs/by-name/pd/pdfium/darwin-27-failing-embedder-tests.txt
new file mode 100644
index 000000000000..a47b7d21d8f5
--- /dev/null
+++ b/pkgs/by-name/pd/pdfium/darwin-27-failing-embedder-tests.txt
@@ -0,0 +1,77 @@
+CPDFSecurityHandlerEmbedderTest.Bug1124998
+CPDFSecurityHandlerEmbedderTest.OwnerPasswordVersion2Latin1
+CPDFSecurityHandlerEmbedderTest.OwnerPasswordVersion2UTF8
+CPDFSecurityHandlerEmbedderTest.OwnerPasswordVersion3Latin1
+CPDFSecurityHandlerEmbedderTest.OwnerPasswordVersion3UTF8
+CPDFSecurityHandlerEmbedderTest.OwnerPasswordVersion5Latin1
+CPDFSecurityHandlerEmbedderTest.OwnerPasswordVersion5UTF8
+CPDFSecurityHandlerEmbedderTest.OwnerPasswordVersion6Latin1
+CPDFSecurityHandlerEmbedderTest.OwnerPasswordVersion6UTF8
+CPDFSecurityHandlerEmbedderTest.PasswordAfterGenerateSave
+CPDFSecurityHandlerEmbedderTest.UserPasswordVersion2Latin1
+CPDFSecurityHandlerEmbedderTest.UserPasswordVersion2UTF8
+CPDFSecurityHandlerEmbedderTest.UserPasswordVersion3Latin1
+CPDFSecurityHandlerEmbedderTest.UserPasswordVersion3UTF8
+CPDFSecurityHandlerEmbedderTest.UserPasswordVersion5Latin1
+CPDFSecurityHandlerEmbedderTest.UserPasswordVersion5UTF8
+CPDFSecurityHandlerEmbedderTest.UserPasswordVersion6Latin1
+CPDFSecurityHandlerEmbedderTest.UserPasswordVersion6UTF8
+FPDFAnnotEmbedderTest.AddAndModifyImage
+FPDFAnnotEmbedderTest.AddAndModifyPath
+FPDFAnnotEmbedderTest.AddAndModifyText
+FPDFAnnotEmbedderTest.AddAndSaveLinkAnnotation
+FPDFAnnotEmbedderTest.AnnotationBorderRendering
+FPDFAnnotEmbedderTest.FocusableAnnotRendering
+FPDFAnnotEmbedderTest.GetSetStringValue
+FPDFAnnotEmbedderTest.ModifyRectQuadpointsWithAP
+FPDFAnnotEmbedderTest.SetFontColor
+FPDFEditEmbedderTest.AddExistingMarkCompressedStream
+FPDFEditEmbedderTest.AddMarkCompressedStream
+FPDFEditEmbedderTest.AddMarkedText
+FPDFEditEmbedderTest.AddMarkedTextWithFloat
+FPDFEditEmbedderTest.AddStandardFontText
+FPDFEditEmbedderTest.AddStandardFontText2
+FPDFEditEmbedderTest.AddTrueTypeFontText
+FPDFEditEmbedderTest.Bug1574
+FPDFEditEmbedderTest.Bug1893
+FPDFEditEmbedderTest.Bug410996566
+FPDFEditEmbedderTest.Bug461845674
+FPDFEditEmbedderTest.GetAndSetMatrixForFormWithText
+FPDFEditEmbedderTest.ModifyFormObject
+FPDFEditEmbedderTest.PathOnTopOfText
+FPDFEditEmbedderTest.RemoveAllFromStream
+FPDFEditEmbedderTest.RemoveExistingPageObjectSplitStreamsLonely
+FPDFEditEmbedderTest.RemoveExistingPageObjectSplitStreamsNotLonely
+FPDFEditEmbedderTest.RemoveFirstFromSingleStream
+FPDFEditEmbedderTest.RemoveLastFromSingleStream
+FPDFEditEmbedderTest.RemoveMarkedObjectsPrime
+FPDFEditEmbedderTest.RemoveTextObject
+FPDFEditEmbedderTest.RemoveTextObjectWithTwoPagesSharingContentArrayAndResources
+FPDFEditEmbedderTest.RemoveTextObjectWithTwoPagesSharingContentStreamAndResources
+FPDFEditEmbedderTest.RemoveTextObjectWithTwoPagesSharingResourcesDict
+FPDFEditEmbedderTest.SetPositions
+FPDFEditEmbedderTest.SetText
+FPDFEditEmbedderTest.SetTextKeepClippingPath
+FPDFEditEmbedderTest.SetTextRenderMode
+FPDFFlattenEmbedderTest.Bug861842
+FPDFFlattenEmbedderTest.Bug889099
+FPDFFormFillComboBoxFormEmbedderTest.FormComboBoxBiDiLiveEdit
+FPDFFormFillEmbedderTest.Bug1302455EditBothForms
+FPDFFormFillEmbedderTest.Bug1302455EditFirstForm
+FPDFFormFillEmbedderTest.Bug1302455EditSecondForm
+FPDFFormFillEmbedderTest.FormText
+FPDFFormFillEmbedderTest.RemoveFormFieldHighlight
+FPDFFormFillTextFormEmbedderTest.FormTextFieldBiDiLiveEdit
+FPDFPPOEmbedderTest.ImportWithZeroLengthStream
+FPDFParserDecodeEmbedderTest.Bug455199
+FPDFProgressiveRenderEmbedderTest.RenderAnnotWithPause
+FPDFProgressiveRenderEmbedderTest.RenderFormsWithPause
+FPDFProgressiveRenderEmbedderTest.RenderHighlightWithColorScheme
+FPDFProgressiveRenderEmbedderTest.RenderHighlightWithColorSchemeAndConvertFillToStroke
+FPDFProgressiveRenderEmbedderTest.RenderStampWithColorScheme
+FPDFProgressiveRenderEmbedderTest.RenderTextWithColorScheme
+FPDFProgressiveRenderEmbedderTest.RenderWithPause
+FPDFProgressiveRenderEmbedderTest.RenderWithoutPause
+FPDFSaveWithFontSubsetEmbedderTest.SaveWithSubsetMultipleFontsMultipleTexts
+FPDFViewEmbedderTest.RenderBug664284WithNoNativeText
+FPDFViewEmbedderTest.RenderHelloWorldWithFlags
diff --git a/pkgs/by-name/pd/pdfium/package.nix b/pkgs/by-name/pd/pdfium/package.nix
index 66102cb7d717..9b304afdc951 100644
--- a/pkgs/by-name/pd/pdfium/package.nix
+++ b/pkgs/by-name/pd/pdfium/package.nix
@@ -177,6 +177,10 @@ let
     "RetainPtr.SetContains"
   ];
 
+  darwin27FailingEmbedderTests = lib.filter (test: test != "") (
+    lib.splitString "\n" (builtins.readFile ./darwin-27-failing-embedder-tests.txt)
+  );
+
   disabledEmbedderTests = [
     # These assert exact serialized PDF and font-subset output. With system
     # libraries, output differs from upstream's in-tree stack; known
@@ -195,7 +199,9 @@ let
     "FPDFProgressiveRenderEmbedderTest.RenderHighlightWithColorScheme"
     "FPDFProgressiveRenderEmbedderTest.RenderHighlightWithColorSchemeAndConvertFillToStroke"
     "FPDFAnnotEmbedderTest.ModifyRectQuadpointsWithAP"
-  ];
+  ]
+  # Changes to CoreGraphics rendering broke these tests when run on macOS 27+.
+  ++ lib.optionals stdenv.hostPlatform.isDarwin darwin27FailingEmbedderTests;
 
   mkDisabledGtestFilter = disabledTests: "-${lib.concatStringsSep ":" disabledTests}";
   unitTestFilter = mkDisabledGtestFilter disabledUnitTests;