diff --git a/pkgs/development/libraries/ffmpeg/generic.nix b/pkgs/development/libraries/ffmpeg/generic.nix
index a44501fea081..2f4aa73d34e1 100644
--- a/pkgs/development/libraries/ffmpeg/generic.nix
+++ b/pkgs/development/libraries/ffmpeg/generic.nix
@@ -93,7 +93,7 @@
 , withVoAmrwbenc ? withFullDeps && withVersion3 # AMR-WB encoder
 , withVorbis ? withHeadlessDeps # Vorbis de/encoding, native encoder exists
 , withVpx ? withHeadlessDeps && stdenv.buildPlatform == stdenv.hostPlatform # VP8 & VP9 de/encoding
-, withVulkan ? withFullDeps && !stdenv.isDarwin
+, withVulkan ? withSmallDeps && !stdenv.isDarwin
 , withWebp ? withFullDeps # WebP encoder
 , withX264 ? withHeadlessDeps && withGPL # H.264/AVC encoder
 , withX265 ? withHeadlessDeps && withGPL # H.265/HEVC encoder
@@ -707,6 +707,10 @@ stdenv.mkDerivation (finalAttrs: {
   postFixup = optionalString (stdenv.isLinux && withLib) ''
     addOpenGLRunpath ${placeholder "lib"}/lib/libavcodec.so
     addOpenGLRunpath ${placeholder "lib"}/lib/libavutil.so
+  ''
+  # https://trac.ffmpeg.org/ticket/10809
+  + optionalString (versionAtLeast version "5.0" && withVulkan) ''
+    patchelf $lib/lib/libavcodec.so --add-needed libvulkan.so --add-rpath ${lib.makeLibraryPath [ vulkan-loader ]}
   '';
 
   enableParallelBuilding = true;