diff --git a/pkgs/development/python-modules/protobuf-py/default.nix b/pkgs/development/python-modules/protobuf-py/default.nix
new file mode 100644
index 000000000000..8a01100ac9c5
--- /dev/null
+++ b/pkgs/development/python-modules/protobuf-py/default.nix
@@ -0,0 +1,51 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchPypi,
+
+  # build-system
+  uv-build,
+
+  # dependencies
+  protobuf-py-ext,
+}:
+
+buildPythonPackage (finalAttrs: {
+  pname = "protobuf-py";
+  # connectrpc requires this exact version and e2b requires <0.2; bump all three
+  # together.
+  version = "0.1.1";
+  pyproject = true;
+  __structuredAttrs = true;
+
+  # No tag on GitHub for this release: bufbuild/protobuf-py's only tag is v0.2.0,
+  # which connectrpc (`protobuf-py==0.1.1`) and e2b (`<0.2`) do not accept yet.
+  src = fetchPypi {
+    pname = "protobuf_py";
+    inherit (finalAttrs) version;
+    hash = "sha256-a9CKxNjxZhllu+JoVCnXkENwTN0e5yCnqJYXMxdCJAs=";
+  };
+
+  build-system = [
+    uv-build
+  ];
+
+  dependencies = [
+    protobuf-py-ext
+  ];
+
+  pythonImportsCheck = [ "protobuf" ];
+
+  # The test suite is not part of the PyPI sdist and there is no git tag for this
+  # release. Note that protobuf swallows an ImportError from protobuf_ext and
+  # falls back to pure Python, so a broken accelerator would not surface here —
+  # protobuf-py-ext's own pythonImportsCheck is what guards that.
+  doCheck = false;
+
+  meta = {
+    description = "Idiomatic Protocol Buffers for Python";
+    homepage = "https://github.com/bufbuild/protobuf-py";
+    license = lib.licenses.asl20;
+    maintainers = with lib.maintainers; [ mishushakov ];
+  };
+})
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index e4034114f142..e0ae79a0b42a 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -13663,6 +13663,8 @@ self: super: with self; {
   # If a protobuf upgrade causes many Python packages to fail, please pin it here to the previous version.
   protobuf = protobuf7;
 
+  protobuf-py = callPackage ../development/python-modules/protobuf-py { };
+
   protobuf-py-ext = callPackage ../development/python-modules/protobuf-py-ext { };
 
   protobuf3-to-dict = callPackage ../development/python-modules/protobuf3-to-dict { };